منابع مشابه
Claudins in lung diseases
Tight junctions are the most apically localized part of the epithelial junctional complex. They regulate the permeability and polarity of cell layers and create compartments in cell membranes. Claudins are structural molecules of tight junctions. There are 27 claudins known, and expression of different claudins is responsible for changes in the electrolyte and solute permeability in cells layer...
متن کاملClaudins
How so? The emergence of chemical biology in universities and medical schools reflects a transition towards the integration of small molecule synthesis, small molecule screens and informatics with the goal of illuminating principles that underlie biology and disease. This is not drug discovery, but the resulting concepts and technologies can be incorporated by the pharmaceutical industry into t...
متن کاملAsbestos-related Lung Diseases: A Brief Update
Health risks from asbestos exposures have been evaluated, considering past professional histories when exposures at workplaces were higher than today. A linear no-threshold (LNT) model has been applied, although its relevance is unproven. Fibers are often found in the lungs and pleura of deceased people. Fiber findings do not prove that a disease is caused by asbestos. It is reasonable to assum...
متن کاملClaudins reign
The claudin family of integral membrane proteins was identified as the major protein component of the tight junctions in all vertebrates. Since their identification, claudins, and their associated pfam00822 superfamily of proteins have been implicated in a wide variety of cellular processes. Claudin homologs have been identified in invertebrates as well, including Drosophila and C. elegans. Rec...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Respiratory Research
سال: 2011
ISSN: 1465-993X
DOI: 10.1186/1465-9921-12-70